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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e13a5e1445c992e74ecbd1b3ff3280dfc458adc666396fa60bf486a73fe1b5d' 
  AND token = 'znV5/yUwn2C1rfuV1ttkb2Qmf1cDqS3vuynpdRLI0vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}