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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141e0c41d422db6ed1f8854bad45668715f297ef8e8025ed3f82872945610768' 
  AND token = 'XeoVkYWJ0UE75ZuyVNFWFqtZs1yPvhYQJTeDHl1X7mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}