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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4219971a8b3ac35a33f67d126322f5b55c88e27dcadb4bc3facd9167dc80f178' 
  AND token = 'y3GXNYosA5zt4knBJUojnHpGr1tsdP+WpEFkpIn5m7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}