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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7830783512fed2743a73e6d50668bc89dc760ddf886b5cb6687bd9186b14a50' 
  AND token = 'ad+Vcw1xHT2TeAblGQb2RsmF6TMDYG6R1Pppd3aKXCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}