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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b83a534ba4abd8a4127177399866bf49050c2c785141a8ee1e65234e2af75b4' 
  AND token = 'XWmKX3S0kQZd2FAXo2JibvFhE/INqoN5neZGoldTVdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}