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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8657be802ca2084d4170c6aa1a0fa5e45b2cba0178261649355b33a9dfc56e5c' 
  AND token = '1/33sdZzEN9Llu9JsY8aCRFHsXnOIXsMFGgE7dhHezg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}