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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4cbc734228e718e5ad0eaa0648b0b6db006597ea51f68750af46741e772b86c' 
  AND token = 'TsUUkwEfeTIObyqRTrj1OptYdfov2UFgAnhT75b1hOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}