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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e105338cc7ceb48a8f6084e570024e25ba4be2dedd175ef2f34d120b9829765a' 
  AND token = 'bOcX8yewLtaYDi+s3kiKAjkRL+6cWQDX10xv9HwKUWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}