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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d465af0593fe07d142156b37ae8690c8a2c26985f8b6f34a7d11d52f68feac7' 
  AND token = 'SEnEaLS7QpRkQmIWyADUeobajkv3FMN0VblWhFhDoUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}