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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49522df7ee0ada1fee8011dafd2a45decf55fb75bcd3e34842a3656b499ca79c' 
  AND token = '+c3gIGjf6zyuhLmrTtDcazeSgvdF42ozalr8Jom0Qk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}