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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053a1ef4347d624d13c5bcdcf9eda8a57cc4168855284008f76134aedc9b45ee' 
  AND token = 'eG/Oe5SqC2lXv7hyq2kEEE8qg01lUFVIwKJIJ4ZyTFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}