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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388464ec7dfb493b57faa0b0ffd3c04c5512b0987c412837548471a775cb5505' 
  AND token = 'CRMDgd/aUeddIMUXbvHGAL/yZcNFj2g9yel9FDQktgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}