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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be9a2710053ad97fb487678f010f543ba3c6a4b91cd31ed078772763a678f0b7' 
  AND token = 'oI2dGmngTisE+wntr/kQAkJgRItCKA1gDkladOWAwqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}