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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ccb50b6722072aecf7020a5e25d51c0eb15a4f4027a287c24d8517bdc2c22da' 
  AND token = '0YOukwG6HKbzMLPhbHoOoWRpYYXWUw152xJLRNU3i0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}