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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158296ef7dfbcfd2117c1fbb96494f4f0f065810d12ba1419df4502a03445ccc' 
  AND token = 'Uwa5fFjqPh++chimg9kWm34wssUucmiyUhXHzshOHsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}