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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336d47a33c008225771d27a8d909644c0f921d7c9a02409c6ffcff953639cc7c' 
  AND token = '2mIesIzPDw7NjfNgGIZ2R4G4M99sKCSv7qyO2eM+hmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}