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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f042fbc6da119c7a3055b5c2d442dba15a871f8957e5f9584881776add6a2ed' 
  AND token = 'Ivi+L4pUJlIXP6cz7lQe/+FfBBUWDqMyuPf0AlkX+vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}