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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de2c5c67cc32c40d67cd080df120ae0579d467b463c263510725b2d656ae65e' 
  AND token = 'TW0mHRXBSEK4x4jn0L+3r7X3eHqo0ZWqaPRCy6I8PLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}