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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248294f2c91781a70b0849f50138c4cd94f855480078f00841a9cad8093787a5' 
  AND token = '5hBLmqNcxY7Q1ct8WPAMtKzqtsJllb4m5atpVTFm5Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}