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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2caca47f40a2c0281f1f3024397b6efdba608af7e74c351a554fd56dd5a34b2d' 
  AND token = 'tJTjI74A39HIGceVrYHI4i19SkN9nLFAfhPJd96T8IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}