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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7b6c0fbc9123d8522bc2b000bf7a2cf538764b94b40d390882ff0751ebcc44c' 
  AND token = 'Z2tw3Af2liwUIjY9RaMQAq8mxkpKjLzxwoU1Z7tPMZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}