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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b96c12271f91a04128910598ab39caf0bb1e1ea1589c5094d664e44cb9d5360' 
  AND token = 'eRGfZ234ykIqpBut1UtUMiF7GkS9BBiVoxR8Cc7fswE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}