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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e804ea19d05e49bf38455e26cea6a70353121a2ba74b2fae547c6a12a9b80347' 
  AND token = 'ncxNfgtBEFmI/U+iOzYC1s2N2BxhJMFI0vadNBbhytE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}