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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effaad0cec01b43a7047cfaf82af2fc263c1196c4e14e62d8d6f663054b43e37' 
  AND token = 'n4UnERftXyIEhr2id7hxJMk4j9f3sM3h3Qc45ED2QMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}