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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50bbd1a2fb4966a1ebf512591d465e622e75d1740bd4dbcb06efd1b2b015f988' 
  AND token = 'wcuFDnvuXXE0SV/Suv2w4A+mAo6nDLFkVPknXZbBEjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}