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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5267be1f0f30b998a02f54905e5217cb17861eea3f53a12484b71ae947697aca' 
  AND token = '65cx3jYJptJgK5A74iJg5DAtD/E2pUZbCF33wcFBtCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}