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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0919e33c1c09a99fbc1ecfd3e50e316429ece44240848316a62bd6a911404fb' 
  AND token = 'uz6bXDVCtC+DBtsyAO+NfwV7tAjDCjRQDud0q42vHy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}