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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe6ef78723ad22bc7c8cb5fce016eaeac696f2b0ea64a7459fa816d01886662' 
  AND token = '16I09A2zNxxi8/Uc+bm4E57QMUxyjXwkoXbA66YTjEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}