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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a717d3b7d5985c893d85126bab0d5bdd6a3ca1cfd6cbec3635035810ad4cf166' 
  AND token = 'm6dM2JXiRlnIcDfCnKbFI7vQ+wsXy4C6i1/kPDyD3j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}