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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '417d579fb8e0fa96567fdc72e5a0ad9bb2277e90cc9a80f8feeac9a6c93e7b53' 
  AND token = 'l1x/VjTZg2pr7S/TDeiFwE2wALiMi7TBAp/sB/0+5Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}