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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445a66cb5d1cd49f05906250c580dc21c690ad0acbd2f9c98d491db7d738bcd3' 
  AND token = 'vs+PUNCeWcvaksy24LCarUl253WN66vOwRWEe1Ww0Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}