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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a903cea20f6bb67fde75d619d86465b0a18c168009bf711cf7358be427867127' 
  AND token = 'dA4PFVW4C7idUb28PsjHryNVPoUEKZjOLjfoWgSAyM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}