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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f65a96d374f0225835da34f636f72f5f1e2b39b71117f167fd1dd8b0e9a97d2' 
  AND token = 'gKHFB3fSIDkHS+/aVGActEAJcrVJP8uI/0sEy6oXUno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}