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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8cdc8128385e0b402cdba0caf5cac7dab2b279533bb833dbe0906d18b849aa' 
  AND token = '5kubRII4EeOTzlfbqc4dZ1yQNwTK4INqB7/wLs1vInE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}