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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee80fc3d3fb16b566f2a875cd811f7bb23403e55efbbf993029791d3c0b364be' 
  AND token = 'IR3a0+NMyl4rwKgfjQC9OjuY5OkSuw0Bufwd1wOEOlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}