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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c9c30abf771a329fc61ca0678a2dd145c0ffc3af0710f5beee3fca9b0668aab' 
  AND token = 'PPLzMQXJ+gxFIornWc5qXcuC/YR8mo/p8mT15ext/G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}