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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542a7b76fb9812ffe367341ad8e72ab7bb3224a372e391888314c79bff2aba02' 
  AND token = 'jiQV+tfpmTy2vQhE/1vzPq3bIkESvVM0J9ongF9klcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}