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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef01fae3ebe6bd049fbe1b1e79d004196d0a657c108a5a1b788aff8710d134f3' 
  AND token = 'hJUCRTiw7S6C7VE/3eOIAqOR8Angjos+hMCPDF5uxf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}