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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b479c537841ba9f38b912e8842956928c8243e58c1b672e1988660e4398b0db2' 
  AND token = 'VkUJj67QzGAh+JRoqEyJ4//3VJUyMbT0xn6kR2a9e5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}