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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39036afefed644c602c0bd933014801e9756269d8cc8c9564b4226c3f810f9e6' 
  AND token = 'tUCYQfDUS8QSwshDajh02fI3r8JNo/b8gDrB59h6eoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}