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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed6a115a19905b722bad2a5a6c0eeedcee30cd412af280ca7d1a5a6c1d1c2eb' 
  AND token = 'H4XJI9d4P09Di1nQFCOoBNzOdveoKLxWpxKUcz9sN0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}