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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e15c7a746c42361db0695467c8b75783159f88cd79544776e50051e56403c6a' 
  AND token = 'bHgBnJ5l7dIhEbDn+P3gpwlYU0kxZYb1jpFzu2AXSdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}