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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72ad83a8e9ea2615133e31205e9f2646c75d69b4a2ce48c0f0a75ea3576805a' 
  AND token = 'IXwpgvS8Zdr8OHFZIKBGX10yAhyiwpMsMo4f7f6JYes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}