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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954f5f248f15cccd30599fddac26830828bce1a9f8cc89f3487ba98242cd11ef' 
  AND token = 'jT2DPGqTprJdtphPlBd/FeFR4wvo7NQt0wPFKDw/jGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}