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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af68f385af151fb4f4d6be54bc8ee909b73e47ac3cf31ac1c7b19223cc0e61f5' 
  AND token = 'cP0DSbjCynX/1JBOMj5hCFDDsjQVnjZBEMpVNu6KIUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}