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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e149ddc5b139c223d8f5a43009cbf8a3e8860302c62c5c8471921e5dc8a801e2' 
  AND token = 'c0U3Aopp749qYYlGWQ1CqJTdh7+QNZfgiRHSESzmle4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}