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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b63a13083ee840d9b542d8f6be24a0be6346b17ef6c82494f86d3d032ab4c2f' 
  AND token = 'F4W6xg0OFRVROdsR3rG5JyfyK67FlOHchWceltEPNOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}