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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3452086608e29de038f3bd02be6372739ea29e641e9d4c999f0346a160e84770' 
  AND token = 'hst+RWZYeYPupdM09XzqS0g9RTiUD1i5RDyAWsXG4ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}