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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e720c0b19658ac8ca5590e8a7562198d8bd5fe0e004b33c0e64a5f185e08862' 
  AND token = 'syx2VbNCpBPeEeVWwBbyhcChWp8pdQGz3CvbxzTRprE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}