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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d92e39fb55d3b3b6f2756bac3be3278b4665946530bd0989236e4ab1a18483' 
  AND token = 'lUR00WVmFCYcnGwflMwocIY/r9eG9N3g7sB5ewSm/js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}